Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62548.1PFAM: NifU-like domain; COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: ssm:Spirs_4302 nitrogen-fixing NifU domain protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; SPTR: Nitrogen-fixing NifU domain protein. (74 aa)    
Predicted Functional Partners:
AEJ61899.1
PFAM: Aminotransferase class-V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: sta:STHERM_c15870 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Cysteine desulfurase.
 
 
 0.794
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
  
 0.778
AEJ60875.1
PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: sta:STHERM_c05760 hypothetical protein; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold.
  
 
 0.734
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 0.715
ilvD
PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: sta:STHERM_c14560 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.661
AEJ61866.1
PFAM: Domain of unknown function (DUF362); COGs: COG2006 conserved hypothetical protein; InterPro IPR007160:IPR001450; KEGG: sta:STHERM_c15570 iron-sulfur cluster-binding protein; PFAM: Protein of unknown function DUF362; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein.
  
  
 0.643
AEJ62549.1
PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase; COGs: COG1816 Adenosine deaminase; HAMAP: Adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: sta:STHERM_c22540 adenosine deaminase; PFAM: Adenosine/AMP deaminase; SPTR: Adenosine deaminase; TIGRFAM: Adenosine deaminase.
       0.607
AEJ62547.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c22520 hypothetical protein; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Putative uncharacterized protein.
       0.569
AEJ62546.1
parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; COGs: COG1475 transcriptional regulator protein; InterPro IPR004437:IPR003115; KEGG: sta:STHERM_c22510 chromosome 1-partitioning protein ParB; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein.
       0.559
AEJ60986.1
PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: sta:STHERM_c15140 hypothetical protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Putative uncharacterized protein; manually curated.
  
  
 0.469
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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