Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ62549.1PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase; COGs: COG1816 Adenosine deaminase; HAMAP: Adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: sta:STHERM_c22540 adenosine deaminase; PFAM: Adenosine/AMP deaminase; SPTR: Adenosine deaminase; TIGRFAM: Adenosine deaminase. (353 aa)    
Predicted Functional Partners:
AEJ62523.1
PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); COGs: COG0813 Purine-nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; InterPro IPR004402:IPR000845; KEGG: sta:STHERM_c22230 purine nucleoside phosphorylase DeoD-type; PFAM: Nucleoside phosphorylase; SPTR: Purine-nucleoside phosphorylase; TIGRFAM: Purine nucleoside phosphorylase.
    
 0.912
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.909
AEJ61319.1
PFAM: Multi-copper polyphenol oxidoreductase laccase; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: sta:STHERM_c10220 inner membrane protein; PFAM: Multi-copper polyphenol oxidoreductase, laccase; SPTR: Putative uncharacterized protein.
    
  0.902
AEJ62548.1
PFAM: NifU-like domain; COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: ssm:Spirs_4302 nitrogen-fixing NifU domain protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; SPTR: Nitrogen-fixing NifU domain protein.
       0.607
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
 0.564
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.525
AEJ62546.1
parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; COGs: COG1475 transcriptional regulator protein; InterPro IPR004437:IPR003115; KEGG: sta:STHERM_c22510 chromosome 1-partitioning protein ParB; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein.
       0.440
AEJ62547.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c22520 hypothetical protein; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Putative uncharacterized protein.
       0.440
AEJ62326.1
RCC1 repeats protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; KEGG: sta:STHERM_c20190 RCC1 repeats protein; SPTR: Regulator of chromosome condensation RCC1.
    
 
 0.407
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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