STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61441.1Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Bacterial transcriptional activator domain; Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c11390 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein; tmRNA as predicted by Rfam (RF00023), score 155.20. (194 aa)    
Predicted Functional Partners:
AEJ60956.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c06620 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 0.807
AEJ60412.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR019734; KEGG: sta:STHERM_c01370 lipoprotein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 0.771
AEJ61176.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR011717:IPR013105:IPR019734; KEGG: sta:STHERM_c08780 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 0.767
AEJ60955.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR019734; KEGG: sta:STHERM_c06600 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
   0.723
AEJ61275.1
Tetratricopeptide TPR_2 repeat-containing protein; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR013105:IPR011717:IPR001440:IPR019734; KEGG: sta:STHERM_c09780 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-4; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
  
     0.715
AEJ60954.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Restriction endonuclease; Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR007560:IPR019734; KEGG: sta:STHERM_c06610 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Restriction endonuclease, type IV-like, Mrr; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
     0.680
AEJ61633.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; COGs: COG2956 N-acetylglucosaminyl transferase; InterPro IPR019734:IPR001440:IPR013105; KEGG: sta:STHERM_c08010 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein.
 
 
 0.668
AEJ61439.1
PEGA domain protein; PFAM: Formylglycine-generating sulfatase enzyme; PEGA domain; COGs: COG1262 conserved hypothetical protein; InterPro IPR013229:IPR005532; KEGG: sta:STHERM_c11370 hypothetical protein; PFAM: PEGA; Sulphatase-modifying factor; SPTR: PEGA domain protein.
       0.619
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.613
AEJ61565.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR019734:IPR001440:IPR013105; KEGG: sta:STHERM_c08720 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
   
 0.480
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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