STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM10740.1TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; COGs: COG0560 Phosphoserine phosphatase; InterPro IPR006385:IPR005834; KEGG: mxa:MXAN_2679 HAD family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily subfamily IB hydrolase, TIGR01490; TIGRFAM: HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial. (227 aa)    
Predicted Functional Partners:
AFM14465.1
PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR004552:IPR002123; KEGG: afv:AFLA_046420 1-acylglycerol-3-phosphate acyltransferase (AtaAp), putative; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: RIB40 DNA, SC011; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
    
 0.890
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.823
AFM10741.1
PFAM: DNA polymerase family B; COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006172:IPR006134; KEGG: lbf:LBF_2104 DNA-directed DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, conserved region; SMART: DNA-directed DNA polymerase, family B; SPTR: Putative DNA polymerase.
     
 0.725
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.723
AFM10742.1
Hypothetical protein.
       0.686
AFM10743.1
KEGG: lbf:LBF_3369 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.686
AFM10744.1
Hypothetical protein.
       0.686
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.668
AFM14587.1
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.
  
  
 0.649
hisB
PFAM: Imidazoleglycerol-phosphate dehydratase; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: lbf:LBF_0841 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase; PFAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; manually curated.
  
  
 0.645
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.