STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM11077.1PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative; COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006056:IPR006175; KEGG: tle:Tlet_0269 putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: Putative endoribonuclease L-PSP; TIGRFAM: YjgF-like protein. (125 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 0.796
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
 0.793
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
   
 0.779
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.771
AFM11076.1
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: afw:Anae109_3837 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
       0.561
nnrE
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
  
 0.540
AFM12063.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
   0.422
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.421
AFM11075.1
PFAM: Enoyl-CoA hydratase/isomerase family; COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: lbf:LBF_0327 enoyl-CoA hydratase/carnithine racemase; PFAM: Crotonase, core; SPTR: Enoyl-CoA hydratase/carnithine racemase.
       0.415
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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