STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (368 aa)    
Predicted Functional Partners:
cmk
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
 
 0.994
AFM14475.1
PFAM: Prephenate dehydratase; Chorismate mutase type II; ACT domain; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2; COGs: COG0077 Prephenate dehydratase; InterPro IPR020822:IPR001086:IPR002912; KEGG: prephenate dehydratase; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; SPTR: Prephenate dehydratase.
 
 
 0.991
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.984
AFM12863.1
PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: lbf:LBF_0031 anthranilate synthase subunit II; PFAM: Glutamine amidotransferase class-I, C-terminal; SPTR: Anthranilate synthase component II; TIGRFAM: Glutamine amidotransferase of anthranilate synthase.
 
 
 0.958
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.955
AFM12862.1
PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890; KEGG: mme:Marme_3565 anthranilate synthase; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; SPTR: Probable anthranilate synthase component I.
 
 
 0.954
AFM13641.1
PFAM: chorismate binding enzyme; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR015890; KEGG: hiq:CGSHiGG_09550 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; SPTR: Aminodeoxychorismate synthase, component I.
 
 
 0.902
AFM12989.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: tcu:Tcur_4391 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: 2-ox [...]
   
 
 0.881
AFM14544.1
PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: mta:Moth_1333 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: TyrA.
  
 
 0.855
AFM14627.1
PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: ava:Ava_4334 histidinol phosphate aminotransferase; PFAM: Aminotransferase, class I/II; SPTR: Histidinol-phosphate aminotransferase 1.
 
  
 0.853
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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