STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM11754.1Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003018:IPR001054; KEGG: lbf:LBF_0606 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; SPTR: Putative adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1028 aa)    
Predicted Functional Partners:
AFM11763.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; 7TM diverse intracellular signalling; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR006104; KEGG: ter:Tery_2857 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Glycoside hydrolase family 2, carbohydrate-binding; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase.
 
    0.781
AFM11490.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: lbf:LBF_3192 adenylate cyclase-like protein; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Putative adenylate cyclase; putative membrane protein.
 
    0.761
AFM11975.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; 7TM diverse intracellular signalling; 7TMR-DISM extracellular 2; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR011622:IPR011623; KEGG: lil:LA_3843 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Diverse 7TM receptor, transmembrane region; Diverse 7TM receptor, extracellular region 2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase.
 
    0.750
AFM13392.1
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: Adenylate and Guanylate cyclase catalytic domain; HAMP domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003660:IPR001054; KEGG: lbf:LBF_4140 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SPTR: Adenylate/guanylate cyclase.
 
    0.748
AFM13458.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; 7TM diverse intracellular signalling; 7TMR-DISM extracellular 2; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR011623:IPR001054; KEGG: lil:LA_3843 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Diverse 7TM receptor, transmembrane region; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase.
 
    0.712
AFM11802.1
Putative transcriptional regulator, Crp/Fnr family; PFAM: Ion transport protein; Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR005821; KEGG: lbf:LBF_1820 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; Ion transport; SMART: Cyclic nucleotide-binding; SPTR: Putative cyclic-nucleotide-gated cation channel; putative membrane protein.
 
 
 0.684
AFM12039.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; Sensors of blue-light using FAD; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007024; KEGG: ngr:NAEGRDRAFT_70440 BLUF domain-containing soluble adenylate/guanylate cyclase; PFAM: BLUF; Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Beta subunit of photoactivated adenylyl cyclase.
 
    0.684
AFM12170.1
Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: sta:STHERM_c06300 hypothetical protein; PFAM: Cyclic nucleotide-binding; SMART: Cyclic nucleotide-binding; SPTR: Putative transcriptional regulator, Crp/Fnr family.
 
 
 0.621
AFM12337.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR000014:IPR003661:IPR003594:IPR001789:IPR0136 56; KEGG: nde:NIDE0815 putative hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; PAS fold-4; Signal transduction response regulator, receiver region; SMART: ATP-binding region, AT [...]
  
 
 0.608
AFM11794.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000014:IPR001789:IPR001610:IPR003661:IPR003594:IPR0136 55; KEGG: sus:Acid_4959 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold-3; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgr [...]
   
 
 0.602
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.