STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM12693.1PFAM: Adenylate and Guanylate cyclase catalytic domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: lbf:LBF_2877 adenylate cyclase family protein; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: PAS fold family. (498 aa)    
Predicted Functional Partners:
AFM11124.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; Heme NO binding associated; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003018:IPR001054; KEGG: lbf:LBF_2448 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; SPTR: Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
 
     0.762
AFM12036.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: lbf:LBF_0897 two component response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Putative two-component response regulator.
 
  
   0.719
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.651
AFM11037.1
MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: pla:Plav_3121 MazG family protein; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial.
     
  0.650
AFM11846.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.650
AFM13748.1
PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794; KEGG: lbl:LBL_4267 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.650
AFM12695.1
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: Adenylate and Guanylate cyclase catalytic domain; HAMP domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003660:IPR001054; KEGG: mgm:Mmc1_1583 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SPTR: Adenylate/guanylate cyclase.
 
    
0.631
AFM12530.1
Integral membrane sensor hybrid histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Stage II sporulation protein E (SpoIIE); COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594:IPR001789:IPR001932:IPR0108 22; KEGG: lbf:LBF_0920 two component response regulator sensor histidine kinase/response regulator subunits; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction response regulator, receiver region; ATP-binding reg [...]
 
   0.627
AFM12694.1
PFAM: Protein of unknown function (DUF2937); KEGG: ote:Oter_1694 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.620
AFM13126.1
Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
  0.611
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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