STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM13282.1Thiamine-phosphate diphosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: psa:PST_3757 thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase. (216 aa)    
Predicted Functional Partners:
AFM12225.1
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004399; KEGG: cag:Cagg_3167 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2.
 
 
 0.995
AFM12673.1
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.981
AFM13657.1
Thiamine-phosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR000728; KEGG: rah:Rahaq_3375 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; SPTR: Thiamine-monophosphate kinase.
    
 0.934
rsgA
Ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
 0.910
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.906
AFM14784.1
De-hypoxanthine futalosine cyclase; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050:IPR006638:IPR007197; KEGG: lbl:LBL_1039 thiamine biosynthesis enzyme; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Thiamine biosynthesis enzyme; TIGRFAM: FO synthase, subunit 2.
  
  
 0.893
AFM14470.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: aba:Acid345_1317 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Sulfur carrier protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis.
  
  
 0.883
AFM10707.1
UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family; InterPro IPR000594; KEGG: sat:SYN_01833 HesA/MoeB/ThiF type protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: HesA/moeB/thiF type protein.
  
  
 0.514
AFM11417.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: rsk:RSKD131_1938 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: Probable molybdopterin biosynthesis protein.
  
  
 0.514
AFM13130.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: svo:SVI_1923 molybdenum cofactor biosynthesis protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: Molybdenum cofactor biosynthesis protein.
  
  
 0.514
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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