STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM13931.1Integrase family protein; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107:IPR002104; KEGG: tjr:TherJR_1462 integrase family protein; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Integrase family protein; Belongs to the 'phage' integrase family. (366 aa)    
Predicted Functional Partners:
AFM13303.1
PFAM: Phage integrase family; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bhy:BHWA1_02688 integrase; PFAM: Integrase, catalytic core, phage; SPTR: Integrase.
  
     0.741
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.565
AFM10873.1
Cell division FtsK/SpoIIIE; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: lbf:LBF_1339 cell division protein with ATPase domain; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: ATPase, AAA+ type, core; SPTR: DNA translocase ftsK; putative membrane protein; Belongs to the FtsK/SpoIIIE/SftA family.
 
   
 0.489
AFM12187.1
Hypothetical protein; COGs: COG1040 amidophosphoribosyltransferase; KEGG: chl:Chy400_1996 amidophosphoribosyltransferase-like protein; SPTR: Amidophosphoribosyltransferase-like protein.
   
    0.487
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.479
ruvB
Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
  
 0.474
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.473
AFM14544.1
PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: mta:Moth_1333 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: TyrA.
  
    0.468
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.460
AFM12078.1
Protein of unknown function DUF159; PFAM: Uncharacterised ACR, COG2135; COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: lbf:LBF_2897 hypothetical protein; PFAM: Protein of unknown function DUF159; SPTR: Putative uncharacterized protein; Belongs to the SOS response-associated peptidase family.
   
  
 0.459
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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