STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM14442.1TIGRFAM: siroheme synthase, N-terminal domain; COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: lbf:LBF_1135 siroheme synthase; SPTR: Siroheme synthetase, N-terminal domain protein; TIGRFAM: Sirohaem synthase, N-terminal. (206 aa)    
Predicted Functional Partners:
AFM14441.1
uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878; KEGG: rce:RC1_2177 siroheme synthase; PFAM: Tetrapyrrole methylase; SPTR: Siroheme synthase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal.
 
 0.999
AFM14443.1
Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067; KEGG: lbl:LBL_0234 sulfite reductase subunit beta; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SPTR: Sulfite reductase (NADPH), alpha subunit.
 
  
 0.949
AFM14438.1
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite.
 
  
 0.920
AFM14439.1
Sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: sulfate adenylyltransferase, small subunit; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: lbf:LBF_1140 sulfate adenylyltransferase subunit 2; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Sulfate adenylyltransferase subunit 2.
  
  
 0.885
AFM14440.1
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.850
AFM14759.1
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.795
AFM13381.1
PFAM: Delta-aminolevulinic acid dehydratase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: porphobilinogen synthase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; SPTR: Porphobilinogen synthase; Belongs to the ALAD family.
 
   
 0.708
hemL
PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; InterPro IPR005814; KEGG: phe:Phep_3448 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase.
 
   
 0.578
AFM11549.1
Glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: lbf:LBF_4066 glutamate synthase (NADH); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase large chain.
      
 0.507
AFM12772.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.491
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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