STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)    
Predicted Functional Partners:
AFM11310.1
PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362:IPR019468:IPR004769; KEGG: lbj:LBJ_0845 adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.997
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.992
purH
PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); HAMAP: Bifunctional purine biosynthesis protein purH; InterPro IPR002695:IPR013982:IPR011607; KEGG: cja:CJA_2747 bifunctional purine biosynthesis protein PurH; PFAM: AICARFT/IMPCHase bienzyme, formylation region; MGS-like; SMART: AICARFT/IMPCHase bienzyme, formylation region; SPTR: Bifunctional purine biosynthesis protein purH; TIGRFAM: AICARFT/IMPCHas [...]
  
 0.965
AFM13823.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: drm:Dred_2376 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.939
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.936
argG
PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: lbf:LBF_0087 argininosuccinate synthase; PFAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.934
pyrB
PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR002082:IPR006132:IPR006131; KEGG: lbf:LBF_0992 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamo [...]
  
 
 0.932
AFM10775.1
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lbf:LBF_2463 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II; SPTR: Aspartate aminotransferase A (Transaminase A; AspAT).
  
 0.920
AFM10977.1
PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR000583:IPR001962; KEGG: bbr:BB0136 putative asparagine synthetase; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II; SPTR: Putative uncharacterized protein; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing.
  
 
 0.916
AFM10984.1
PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR000583:IPR001962; KEGG: dba:Dbac_3261 asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; Glutamine amidotransferase, class-II; SPTR: Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing.
  
 
 0.916
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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