STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1A0HI13Saccharopine dehydrogenase. (445 aa)    
Predicted Functional Partners:
A0A1A0HHV3
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.
  
 
 0.935
A0A1A0HDQ7
Spermine synthase; Belongs to the spermidine/spermine synthase family.
   
 0.933
A0A1A0H989
Large subunit of L-aminoadipate-semialdehyde dehydrogenase.
  
 
 0.889
A0A1A0H565
Spermine synthase; Belongs to the spermidine/spermine synthase family.
   
 0.863
A0A1A0HDF6
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.854
A0A1A0HJB4
S-adenosylmethionine decarboxylase.
     
 0.805
MEU1
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
  0.788
A0A1A0HIP4
Isocitrate/isopropylmalate dehydrogenase.
   
  
 0.780
A0A1A0H8E2
Argininosuccinate lyase.
 
 
  
 0.653
A0A1A0H758
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
   
  
 0.623
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
Server load: low (8%) [HD]