Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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EIJ32987.1Sodium/proton antiporter, CPA1 family; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153:IPR003148; KEGG: pag:PLES_12411 putative sodium/hydrogen antiporter; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Transporter, CPA2 family; (TC 2.A.36). (599 aa)    
Predicted Functional Partners:
EIJ32985.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 001757; KEGG: app:CAP2UW1_4071 HAD superfamily P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase [...]
    
 
 0.636
EIJ32988.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase; COGs: COG0461 Orotate phosphoribosyltransferase; HAMAP: Orotate phosphoribosyltransferase; InterPro IPR000836:IPR004467; KEGG: tgr:Tgr7_0108 orotate phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: Orotate phosphoribosyl transferase.
       0.555
EIJ34356.1
PFAM: Ras family; TIGRFAM: small GTP-binding protein domain; COGs: COG1100 GTPase SAR1 and related small G protein; InterPro IPR003577:IPR003579:IPR013753:IPR005225; KEGG: npu:Npun_F1893 small GTP-binding protein; PFAM: Ras; SMART: Ras small GTPase, Rab type; Ras small GTPase, Ras type; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
  
 
 0.525
EIJ33707.1
PFAM: Domain of unknown function DUF29; InterPro IPR002636; KEGG: pay:PAU_03740 hypothetical protein; PFAM: Protein of unknown function DUF29; SPTR: Putative uncharacterized protein.
    
   0.499
EIJ34238.1
PFAM: Domain of unknown function DUF29; InterPro IPR002636; KEGG: amv:ACMV_P2_00480 hypothetical protein; PFAM: Protein of unknown function DUF29; SPTR: Putative uncharacterized protein.
    
   0.499
EIJ34647.1
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: bis(5'-nucleosyl)-tetraphosphatase (symmetrical); HAMAP: Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; InterPro IPR004843:IPR004617; KEGG: tgr:Tgr7_2728 diadenosine tetraphosphatase; PFAM: Metallophosphoesterase; SPTR: Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; TIGRFAM: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
    
   0.499
EIJ36596.1
PFAM: Domain of unknown function DUF29; InterPro IPR002636; KEGG: dze:Dd1591_3729 hypothetical protein; PFAM: Protein of unknown function DUF29; SPTR: Putative uncharacterized protein.
    
   0.499
EIJ36672.1
PFAM: Domain of unknown function DUF29; InterPro IPR002636; KEGG: cyj:Cyan7822_3948 hypothetical protein; PFAM: Protein of unknown function DUF29; SPTR: Putative uncharacterized protein.
    
   0.499
EIJ33105.1
Hypothetical protein; PFAM: Ras family; KEGG: npu:Npun_F6039 Miro domain-containing protein; SPTR: Miro domain protein.
    
 0.459
EIJ32777.1
Kef-type potassium/proton antiporter, CPA2 family; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153:IPR003148; KEGG: msl:Msil_2332 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; (TC 2.A.37.1).
   
 
 0.400
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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