STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIJ33124.1GTP-binding protein HSR1-related protein; PFAM: GTPase of unknown function; Domain of unknown function (DUF697); InterPro IPR002917; KEGG: dno:DNO_0575 hypothetical protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Putative uncharacterized protein. (505 aa)    
Predicted Functional Partners:
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
   0.909
mnmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
    
 
 0.903
EIJ33643.1
23S rRNA Gm-2251 2'-O-methyltransferase; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537:IPR004441; KEGG: rsc:RCFBP_20204 tRNA guanosine-2'-O-methyltransferase; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SPTR: tRNA guanosine-2'-O-methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3.
   
 
 0.897
rplQ
PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; COGs: COG0203 Ribosomal protein L17; HAMAP: 50S ribosomal protein L17; InterPro IPR000456; KEGG: tkm:TK90_2143 ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17.
   
   0.897
EIJ36402.1
Iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein; COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: tgr:Tgr7_2274 iojap-like protein; PFAM: Iojap-related protein; SPTR: Iojap-like protein; TIGRFAM: Iojap-related protein.
    
 
 0.895
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.894
EIJ34608.1
PFAM: tRNA pseudouridine synthase D (TruD); TIGRFAM: tRNA pseudouridine synthase, TruD family; COGs: COG0585 conserved hypothetical protein; HAMAP: tRNA pseudouridine synthase D; InterPro IPR001656; KEGG: tcx:Tcr_0216 pseudouridylate synthase; PFAM: Pseudouridine synthase, TruD; SPTR: tRNA pseudouridine synthase D; TIGRFAM: Pseudouridine synthase, TruD.
    
   0.892
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
   0.887
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
   0.885
rplX
LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
   0.885
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.