Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIJ33301.1PFAM: UvrD/REP helicase; TIGRFAM: exodeoxyribonuclease V, beta subunit; COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR004586:IPR000212; KEGG: psa:PST_4033 exodeoxyribonuclease V, beta subunit; PFAM: DNA helicase, UvrD/REP type; SPTR: Exodeoxyribonuclease V, beta subunit; TIGRFAM: Exodeoxyribonuclease V, beta subunit. (1188 aa)    
Predicted Functional Partners:
EIJ33029.1
DNA helicase/exodeoxyribonuclease V, alpha subunit; PFAM: UvrD/REP helicase; Viral (Superfamily 1) RNA helicase; TIGRFAM: exodeoxyribonuclease V, alpha subunit; helicase, putative, RecD/TraA family; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR000212:IPR006344:IPR003593; KEGG: cph:Cpha266_1400 DNA helicase/exodeoxyribonuclease V, alpha subunit; PFAM: DNA helicase, UvrD/REP type; SMART: ATPase, AAA+ type, core; SPTR: DNA helicase/exodeoxyribonuclease V, alpha subunit; TIGRFAM: Exodeoxyribonuclease V, alpha subunit.
 
 0.997
EIJ35979.1
PFAM: Exodeoxyribonuclease V, gamma subunit; TIGRFAM: exodeoxyribonuclease V, gamma subunit; COGs: COG1330 Exonuclease V gamma subunit; InterPro IPR006697; KEGG: cvi:CV_4077 exodeoxyribonuclease V subunit gamma; PFAM: Exodeoxyribonuclease V, RecC subunit; SPTR: Exodeoxyribonuclease V, gamma subunit; TIGRFAM: Exodeoxyribonuclease V, RecC subunit.
 
 0.995
EIJ35275.1
Hypothetical protein; PFAM: PIF1 helicase; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; KEGG: cyc:PCC7424_5834 DNA helicase; SPTR: DNA helicase, putative.
  
 
 0.856
EIJ33146.1
PFAM: Domain of unknown function (DUF1877); InterPro IPR015068; KEGG: dal:Dalk_5077 hypothetical protein; PFAM: Protein of unknown function DUF1877; SPTR: Putative uncharacterized protein.
  
 
 0.673
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.602
EIJ35577.1
ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001:IPR001650:IPR002121:IPR006293:IPR 018329:IPR011545:IPR018982; KEGG: tgr:Tgr7_1931 ATP-dependent DNA helicase RecQ; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal [...]
    
 0.567
EIJ33037.1
PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR004365:IPR004805:IPR 003141; KEGG: tgr:Tgr7_1176 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit.
  
  
 0.553
EIJ36021.1
DNA replication and repair protein RecR; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR; COGs: COG0353 Recombinational DNA repair protein (RecF pathway); HAMAP: Recombination protein recR; InterPro IPR006154:IPR000093:IPR015967:IPR006171; KEGG: tgr:Tgr7_1075 recombination protein RecR; PFAM: Toprim domain; Zinc finger C4-type, RecR; SMART: Toprim domain, subgroup; SPTR: Recombination protein recR; TIGRFAM: RecR protein.
     
 0.483
EIJ32978.1
Excinuclease ABC subunit C; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit; COGs: COG0322 Nuclease subunit of the excinuclease complex; HAMAP: UvrABC system protein C; InterProIPR004791:IPR000305:IPR001943:IPR001162:IPR 000445; KEGG: tgr:Tgr7_1907 excinuclease ABC subunit C; PFAM: Excinuclease ABC, C subunit, C-terminal; Excinuclease ABC, C subunit, N-terminal; UvrB/UvrC protein; Helix-hairpin-helix motif; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: UvrABC system protein C; TIGRFAM: Excinuclease ABC, [...]
     
 0.482
ruvC
Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
     
 0.481
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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