STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIJ33597.1Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: lhk:LHK_00468 transcriptional regulator, fis family; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Possible transcriptional regulator, fis family. (297 aa)    
Predicted Functional Partners:
EIJ33599.1
Methionine synthase (B12-independent); PFAM: Cobalamin-independent synthase, Catalytic domain; Cobalamin-independent synthase, N-terminal domain; TIGRFAM: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; COGs: COG0620 Methionine synthase II (cobalamin-independent); HAMAP:5-methyltetrahydropteroyltriglutamate--homocy steineS-methyltransferase; InterPro IPR013215:IPR002629:IPR006276; KEGG: mfa:Mfla_2571 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin (vitamin B12)-independent me [...]
 
  
 0.780
EIJ33598.1
SMC domain protein; COGs: COG4637 ATPase; InterPro IPR003395; KEGG: dze:Dd1591_3645 SMC domain-containing protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: SMC domain protein.
       0.773
EIJ35494.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: mmt:Metme_2072 LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family.
  
     0.569
EIJ34771.1
Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: mci:Mesci_1344 LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: LysR substrate-binding protein.
  
     0.547
EIJ33596.1
Protein of unknown function UPF0061; PFAM: Uncharacterized ACR, YdiU/UPF0061 family; COGs: COG0397 conserved hypothetical protein; InterPro IPR003846; KEGG: amr:AM1_5878 hypothetical protein; PFAM: Uncharacterised protein family UPF0061; SPTR: Putative uncharacterized protein.
       0.466
EIJ36681.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: hmo:HM1_1037 glutamate synthase [nadph] large chain; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase [nadph] large chain.
     
 0.435
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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