STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIJ33723.1PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1; COGs: COG0216 Protein chain release factor A; HAMAP: Peptide chain release factor 1; InterPro IPR005139:IPR000352:IPR004373; KEGG: tgr:Tgr7_0522 peptide chain release factor 1; PFAM: Class I peptide chain release factor; Peptide chain release factor; SPTR: Peptide chain release factor 1; TIGRFAM: Peptide chain release factor 1. (359 aa)    
Predicted Functional Partners:
EIJ33724.1
(protein release factor)-glutamine N5-methyltransferase; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; protein-(glutamine-N5) methyltransferase, release factor-specific; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR007848:IPR004556:IPR019874; KEGG: tcx:Tcr_0388 HemK family modification methylase; PFAM: Methyltransferase small; SPTR: Polypeptide chain release factor methylase; TIGRFAM: Protein-(glutamine-N5) methyltransferase, release factor-specific; Modification methylase HemK.
 
 
 0.999
EIJ33499.1
PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20; COGs: COG0292 Ribosomal protein L20; HAMAP: Ribosomal protein L20; InterPro IPR005813; KEGG: tgr:Tgr7_1453 ribosomal protein L20; PFAM: Ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: Ribosomal protein L20.
  
 
 0.997
rpmA
PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: aeh:Mlg_0846 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.997
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.997
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.997
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
 
 
 0.996
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
 
 0.996
rplQ
PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; COGs: COG0203 Ribosomal protein L17; HAMAP: 50S ribosomal protein L17; InterPro IPR000456; KEGG: tkm:TK90_2143 ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17.
 
 
 0.996
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.995
rplD
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
 
 0.995
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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