Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIJ34501.1Helix-turn-helix domain protein; PFAM: Helix-turn-helix; InterPro IPR001387; KEGG: eba:ebD35 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Putative uncharacterized protein. (79 aa)    
Predicted Functional Partners:
EIJ35222.1
PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Transketolase, C-terminal domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR019752:IPR001450:IPR011766; KEGG: alv:Alvin_1172 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate [...]
  
 
  0.875
EIJ36632.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.726
EIJ34283.1
NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR003694; KEGG: tgr:Tgr7_0811 NAD+ synthetase; PFAM: NAD+ synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: NAD+ synthetase; TIGRFAM: NAD+ synthase.
     
  0.722
EIJ34502.1
KEGG: rva:Rvan_2829 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.651
EIJ34996.1
PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: aeh:Mlg_0246 malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme.
     
  0.651
EIJ35657.1
N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; COGs: COG0548 Acetylglutamate kinase; InterPro IPR010167:IPR001048:IPR000182; KEGG: tgr:Tgr7_0572 N-acetylglutamate synthase; PFAM: GCN5-related N-acetyltransferase; Aspartate/glutamate/uridylate kinase; SPTR: Amino-acid acetyltransferase; TIGRFAM: Amino-acid N-acetyltransferase (ArgA).
    
  0.598
EIJ34504.1
PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: ara:Arad_12031 hypothetical protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: HipA domain protein.
  
    0.455
EIJ34500.1
KEGG: mmt:Metme_3540 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.450
EIJ34503.1
Helix-turn-helix domain protein; PFAM: Helix-turn-helix; InterPro IPR001387; KEGG: rlg:Rleg_7007 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family protein.
       0.448
EIJ34724.1
Hypothetical protein; PFAM: NACHT domain; KEGG: scl:sce2280 WD repeat-containing protein; SPTR: Hypothetical WD-repeat protein alr2800.
     
  0.411
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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