Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIJ34557.1PFAM: SPFH domain / Band 7 family; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: csa:Csal_2766 SPFH domain-containing protein/band 7 family protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: SPFH domain, Band 7 family protein. (265 aa)    
Predicted Functional Partners:
EIJ34556.1
Protein of unknown function DUF107; PFAM: NfeD-like; COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: tgr:Tgr7_2129 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Putative uncharacterized protein.
 
    0.963
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.770
EIJ34906.1
Peptidase M41; PFAM: C-terminal, D2-small domain, of ClpB protein; Peptidase family M41; ATPase family associated with various cellular activities (AAA); COGs: COG0465 ATP-dependent Zn protease; InterPro IPR000642; KEGG: vpe:Varpa_2819 peptidase M41; PFAM: Peptidase M41; SPTR: Peptidase M41.
   
  0.755
EIJ35305.1
Protein of unknown function DUF107; PFAM: NfeD-like; COGs: COG1585 Membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: kko:Kkor_2297 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Putative uncharacterized protein.
  
 
 0.755
EIJ34193.1
PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: tgr:Tgr7_2986 hypothetical protein; PFAM: Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Putative uncharacterized protein.
  
  0.664
EIJ34194.1
PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: alv:Alvin_2888 peptidase M16 domain-containing protein; PFAM: Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Peptidase M16 domain protein.
   
  0.659
EIJ35425.1
PFAM: CheB methylesterase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CheR methyltransferase, SAM binding domain; His Kinase A (phosphoacceptor) domain; CheR methyltransferase, all-alpha domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000780:IPR003661:IPR003594:IPR000014:IPR 000673:IPR013767; KEGG: din:Selin_0964 ATPase ATP-binding domain-containing protein; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferas [...]
  
 
  0.640
EIJ34558.1
KEGG: dar:Daro_3465 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.636
EIJ33515.1
PFAM: Cytochrome c; Cytochrome C oxidase subunit II, periplasmic domain; Cytochrome C oxidase subunit II, transmembrane domain; TIGRFAM: cytochrome c oxidase, subunit II; COGs: COG1622 Heme/copper-type cytochrome/quinol oxidase subunit 2; InterPro IPR014222:IPR011759:IPR002429:IPR003088; KEGG: tgr:Tgr7_3011 cytochrome-c oxidase; PFAM: Cytochrome c oxidase subunit II C-terminal; Cytochrome C oxidase subunit II, transmembrane region; Cytochrome c, class I; SPTR: Cytochrome-c oxidase; TIGRFAM: Cytochrome c oxidase, subunit II.
   
   0.607
EIJ34554.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: bra:BRADO3955 OmpR family two-component transcriptional regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component transcriptional regulat [...]
  
    0.532
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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