Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIJ34586.1PFAM: Rhodanese-like domain; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: tkm:TK90_2023 rhodanese; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein. (141 aa)    
Predicted Functional Partners:
EIJ34585.1
PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin, GrxC family; COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109:IPR011900; KEGG: rcp:RCAP_rcc00198 glutaredoxin; PFAM: Glutaredoxin; SPTR: Glutaredoxin 3; TIGRFAM: Glutaredoxin, GrxC.
  
    0.933
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
    
  0.792
EIJ34584.1
PFAM: Preprotein translocase subunit SecB; TIGRFAM: protein-export chaperone SecB; COGs: COG1952 Preprotein translocase subunit SecB; HAMAP: Bacterial protein export chaperone SecB; InterPro IPR003708; KEGG: shm:Shewmr7_0045 preprotein translocase subunit SecB; PFAM: Bacterial protein export chaperone SecB; SPTR: Protein-export protein secB; TIGRFAM: Bacterial protein export chaperone SecB.
  
    0.781
EIJ34897.1
PFAM: Thiazole biosynthesis protein ThiG; COGs: COG2022 Uncharacterized protein of thiazole biosynthesis; HAMAP: Thiazole biosynthesis; InterPro IPR008867; KEGG: tgr:Tgr7_3236 thiazole biosynthesis family protein; PFAM: Thiazole biosynthesis; SPTR: Thiazole synthase.
  
 
 0.779
EIJ34583.1
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; InterPro IPR011128:IPR006109; KEGG: tgr:Tgr7_3281 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal; NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+].
  
    0.757
EIJ36893.1
Cysteine desulfurase NifS; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase NifS; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR017772; KEGG: alv:Alvin_1401 cysteine desulfurase NifS; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Cysteine desulfurase NifS; TIGRFAM: Cysteine desulfurase, NifS, bacterial/archaeal.
    
  0.739
EIJ36529.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.724
EIJ33950.1
O-succinylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine sulfhydrylase; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR006234:IPR000277; KEGG: tkm:TK90_1929 O-succinylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: O-succinylhomoserine sulfhydrylase; TIGRFAM: O-succinylhomoserine sulfhydrylase.
     
  0.722
EIJ34535.1
Methionine gamma-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR006237; KEGG: mgm:Mmc1_0771 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Methionine gamma-lyase; TIGRFAM: Methionine gamma-lyase.
     
  0.722
EIJ36578.1
SmpA/OmlA domain-containing protein; PFAM: SmpA / OmlA family; COGs: COG2913 Small protein A (tmRNA-binding); InterPro IPR007450; KEGG: rfr:Rfer_0754 SmpA/OmlA; PFAM: SmpA/OmlA; SPTR: SmpA/OmlA domain protein.
   
    0.719
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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