STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
EIJ34983.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003661:IPR003594; KEGG: azo:azo2799 two component sensor protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Probable two component sensor protein. (445 aa)    
Predicted Functional Partners:
EIJ34982.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: rso:RSc3087 response regulator transcription regulator protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Probable response regulator transcriptio [...]
 
 0.995
EIJ33924.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Protein of unknown function (DUF3365); PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 001789; KEGG: ami:Amir_2370 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction response regulator, receiver region; SMART: Signal t [...]
 
0.973
EIJ35425.1
PFAM: CheB methylesterase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CheR methyltransferase, SAM binding domain; His Kinase A (phosphoacceptor) domain; CheR methyltransferase, all-alpha domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterProIPR000780:IPR003661:IPR003594:IPR000014:IPR 000673:IPR013767; KEGG: din:Selin_0964 ATPase ATP-binding domain-containing protein; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferas [...]
  
 0.960
EIJ33757.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR001610; KEGG: nhl:Nhal_2031 PAS sensor protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; PAS fold-3; Signal transduction response regulator, receiver region; [...]
 
0.958
EIJ35797.1
Integral membrane sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; 7TMR-DISM extracellular 2; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR011622:IPR003661:IPR003594:IPR001789; KEGG: pmy:Pmen_3766 integral membrane sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Diverse 7TM receptor, extracellular regio [...]
 
0.955
EIJ33756.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: afw:Anae109_1492 histidine kinase; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Histidine kinase.
 0.952
EIJ35532.1
Integral membrane sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; 7TMR-DISM extracellular 2; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR011623; KEGG: pag:PLES_10011 lost adherence sensor, LadS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Diverse 7TM receptor, transmembrane region; Signal transducti [...]
0.951
EIJ33942.1
Integral membrane sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: geb:GM18_3186 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; ATP-bin [...]
 
 
0.949
EIJ33926.1
PFAM: Hpt domain; InterPro IPR008207; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) region; SPTR: Hpt domain protein.
  
 0.939
EIJ33928.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: rru:Rru_A2033 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...]
 
0.870
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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