STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIJ35012.1Peptidase M3A and M3B thimet/oligopeptidase F; PFAM: Peptidase family M3; COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: tgr:Tgr7_0006 oligopeptidase A; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; SPTR: Oligopeptidase A. (690 aa)    
Predicted Functional Partners:
EIJ35011.1
Exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: tgr:Tgr7_0007 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Exodeoxyribonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1.
       0.790
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.787
EIJ35010.1
KEGG: tcy:Thicy_0290 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.781
EIJ35014.1
DNA replication and repair protein RecF; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein; COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); HAMAP: DNA replication and repair protein recF; InterPro IPR003395:IPR001238; KEGG: ebi:EbC_45640 DNA replication and repair protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA-binding, RecF.
  
    0.702
EIJ35015.1
PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit; COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: tgr:Tgr7_0002 DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain.
  
    0.658
EIJ34108.1
PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR007865:IPR000994; KEGG: gpb:HDN1F_01240 Xaa-Pro aminopeptidase; PFAM: Peptidase M24, structural domain; Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal; SPTR: Aminopeptidase P.
  
 
 
 0.458
EIJ33240.1
PFAM: Domain of unknown function (DUF303); InterPro IPR005181; KEGG: sus:Acid_5941 protein of unknown function DUF303, acetylesterase putative; PFAM: Protein of unknown function DUF303, acetylesterase putative; SPTR: Iduronate-2-sulfatase.
     
 0.439
EIJ36423.1
PFAM: alpha/beta hydrolase fold; COGs: COG0657 Esterase/lipase; InterPro IPR013094; KEGG: mdi:METDI2691 alpha/beta hydrolase; SPTR: Alpha/beta hydrolase fold-3 domain protein.
     
 0.439
EIJ35008.1
PFAM: Patatin-like phospholipase; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: dba:Dbac_3078 Patatin; PFAM: Patatin; SPTR: Patatin.
       0.429
EIJ35009.1
Hypothetical protein; KEGG: hdn:Hden_1086 von Willebrand factor A; SPTR: von Willebrand factor type A.
       0.429
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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