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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
EIJ35115.1PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: tgr:Tgr7_0182 Na+/solute symporter; PFAM: Sodium/solute symporter; SPTR: Na+/solute symporter. (472 aa)    
Predicted Functional Partners:
EIJ33926.1
PFAM: Hpt domain; InterPro IPR008207; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) region; SPTR: Hpt domain protein.
  
 
 0.926
EIJ33924.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Protein of unknown function (DUF3365); PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 001789; KEGG: ami:Amir_2370 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction response regulator, receiver region; SMART: Signal t [...]
  
 
 0.898
EIJ35532.1
Integral membrane sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; 7TMR-DISM extracellular 2; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR011623; KEGG: pag:PLES_10011 lost adherence sensor, LadS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Diverse 7TM receptor, transmembrane region; Signal transducti [...]
   
 
 0.894
EIJ35797.1
Integral membrane sensor hybrid histidine kinase; PFAM: 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; 7TMR-DISM extracellular 2; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR011622:IPR003661:IPR003594:IPR001789; KEGG: pmy:Pmen_3766 integral membrane sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Diverse 7TM receptor, extracellular regio [...]
   
 
 0.894
EIJ35117.1
PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006132:IPR006131; KEGG: kko:Kkor_2051 aspartate/ornithine carbamoyltransferase carbamoyl-P-binding domain-containing protein; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; SPTR: Aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain [...]
 
     0.873
EIJ35118.1
PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583:IPR001962:IPR006426; KEGG: syw:SYNW2453 putative asparagine synthetase protein; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II; SPTR: Asparagine synthase; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing.
 
     0.825
EIJ33942.1
Integral membrane sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: geb:GM18_3186 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; ATP-bin [...]
    
 0.823
EIJ33756.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: afw:Anae109_1492 histidine kinase; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Histidine kinase.
   
 
 0.798
EIJ33928.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: rru:Rru_A2033 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...]
   
 
 0.798
EIJ36048.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013656:IPR013655; KEGG: swo:Swol_0601 signal transduction histidine kinase-like protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; PAS fold-3; PAS fold-4; Signal transduction response regulato [...]
   
 
 0.798
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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