STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIJ35348.1PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase; COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455:IPR000304; KEGG: tgr:Tgr7_2920 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: Delta 1-pyrroline-5-carboxylate reductase. (280 aa)    
Predicted Functional Partners:
EIJ35347.1
Protein of unknown function YGGT; PFAM: YGGT family; InterPro IPR003425; KEGG: tgr:Tgr7_2921 hypothetical protein; PFAM: Protein of unknown function YGGT; SPTR: Putative uncharacterized protein.
  
    0.833
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.783
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.752
EIJ35346.1
UPF0235 protein yggU; PFAM: Uncharacterised ACR, YggU family COG1872; TIGRFAM: TIGR00251 family protein; COGs: COG1872 conserved hypothetical protein; HAMAP: Protein of unknown function DUF167; InterPro IPR003746:IPR005228; KEGG: pmk:MDS_4479 hypothetical protein; PFAM: Protein of unknown function DUF167; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00251.
     
 0.709
EIJ36168.1
PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797:IPR004477; KEGG: nhl:Nhal_0530 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein.
 
   
 0.560
EIJ35349.1
PFAM: Protein of unknown function (DUF3301); KEGG: aeh:Mlg_0686 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.555
EIJ36681.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: hmo:HM1_1037 glutamate synthase [nadph] large chain; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase [nadph] large chain.
     
 0.552
EIJ34611.1
PFAM: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; COGs: COG0253 Diaminopimelate epimerase; HAMAP: Diaminopimelate epimerase; InterPro IPR001653; KEGG: alv:Alvin_2089 diaminopimelate epimerase; PFAM: Diaminopimelate epimerase; SPTR: Diaminopimelate epimerase; TIGRFAM: Diaminopimelate epimerase.
     
 0.539
EIJ36307.1
KEGG: hau:Haur_3960 beta-ketoacyl synthase; SPTR: Beta-ketoacyl synthase.
  
  
 0.528
EIJ32768.1
PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase [glutamine-hydrolyzing]; InterPro IPR004739:IPR001674:IPR000991:IPR018318; KEGG: tgr:Tgr7_1036 GMP synthase; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA methyl transferase-like; SPTR: GMP synthase [glutamine-hydrolyzing]; TIGRFAM: GMP syntha [...]
     
 0.521
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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