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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIJ35529.1Nucleoside-triphosphatase rdgB; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; COGs: COG0127 Xanthosine triphosphate pyrophosphatase; HAMAP: Nucleoside-triphosphatase rdgB; InterPro IPR002637; KEGG: ecz:ECS88_3236 deoxyribonucleotide triphosphate pyrophosphatase; PFAM: Ham1-like protein; SPTR: Non-canonical purine NTP pyrophosphatase; TIGRFAM: Ham1-like protein. (196 aa)    
Predicted Functional Partners:
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
 
 
  0.995
EIJ32768.1
PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase [glutamine-hydrolyzing]; InterPro IPR004739:IPR001674:IPR000991:IPR018318; KEGG: tgr:Tgr7_1036 GMP synthase; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA methyl transferase-like; SPTR: GMP synthase [glutamine-hydrolyzing]; TIGRFAM: GMP syntha [...]
 
 
 0.950
EIJ32767.1
PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR005990:IPR001093:IPR000644; KEGG: tgr:Tgr7_1035 inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Inosine-5'-monophosphate dehydrogenase; TIGRFAM: IMP dehydrogenase.
  
 0.924
EIJ35777.1
PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase; COGs: COG0796 Glutamate racemase; HAMAP: Glutamate racemase; InterPro IPR004391:IPR015942; KEGG: pba:PSEBR_a4755 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Glutamate racemase; TIGRFAM: Glutamate racemase.
 
 
  0.921
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.896
EIJ36823.1
Hypothetical protein; KEGG: dmo:Dmoj_GI21589 GI21589 gene product from transcript GI21589-RA; SPTR: GI21589.
  
 0.894
EIJ33304.1
Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836; KEGG: tgr:Tgr7_1752 hypoxanthine-guanine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Hypoxanthine-guanine phosphoribosyltransferase.
   
 
 0.864
EIJ35199.1
TIGRFAM: phosphoesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: alv:Alvin_3086 phosphodiesterase; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025.
  
  
 0.852
EIJ35527.1
PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: tgr:Tgr7_3254 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase.
       0.802
EIJ35528.1
D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family domain; COGs: COG0241 Histidinol phosphatase and related phosphatase; InterPro IPR006543:IPR006549:IPR005834; KEGG: ppw:PputW619_0078 D,D-heptose 1,7-bisphosphate phosphatase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Histidinol-phosphate phosphatase family protein; TIGRFAM: Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA.
     
 0.799
Your Current Organism:
Thiothrix nivea
NCBI taxonomy Id: 870187
Other names: T. nivea DSM 5205, Thiothrix nivea DSM 5205, Thiothrix nivea JP2, Thiothrix nivea str. DSM 5205, Thiothrix nivea strain DSM 5205
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