Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpu_02420DNA-binding response regulator. (251 aa)    
Predicted Functional Partners:
cpu_02430
Histidine kinase.
 
 0.991
cpu_04070
Sensor histidine kinase.
 
 0.962
cpu_04080
DNA-binding response regulator.
  
  
 
0.747
cpu_02410
Carbon starvation protein A.
 
   
 0.646
cpu_07650
Sensor histidine kinase.
    
 0.474
cpu_03310
ABC transporter substrate-binding protein.
    
 0.468
cpu_20790
HDIG domain-containing protein.
    
 0.468
cpu_21230
Hypothetical protein.
  
 
 0.435
cpu_25650
Histidine kinase.
  
 
 0.435
cpu_02440
MBL fold metallo-hydrolase.
       0.426
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
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