STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpu_03210Cation acetate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (509 aa)    
Predicted Functional Partners:
cpu_03200
Hypothetical protein.
 
  
 0.997
cpu_03190
Hypothetical protein.
 
  
 0.801
cpu_00310
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
  
 0.589
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.589
cpu_04930
Hypothetical protein.
  
  
 0.589
cpu_04950
acetate--CoA ligase.
  
  
 0.589
cpu_09200
acyl-CoA synthetase.
  
  
 0.589
cpu_03180
DNA polymerase III subunit epsilon.
 
     0.539
cpu_03220
Copper oxidase.
     
 0.485
cpu_21040
3-hydroxyacyl-CoA dehydrogenase.
   
  
 0.445
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
Server load: low (28%) [HD]