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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpu_04460L-serine dehydratase, iron-sulfur-dependent subunit beta. (218 aa)    
Predicted Functional Partners:
cpu_04470
L-serine dehydratase, iron-sulfur-dependent subunit alpha.
 
 0.999
cpu_23230
L-serine dehydratase, iron-sulfur-dependent subunit alpha.
 
 0.997
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.896
cpu_23250
Threonine ammonia-lyase.
  
 
 0.803
cpu_13090
Threonine ammonia-lyase.
  
 
 0.799
dsdA
D-serine dehydratase; Belongs to the serine/threonine dehydratase family. DsdA subfamily.
     
 0.779
cpu_16440
Serine O-acetyltransferase.
     
 0.772
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.766
cpu_04480
Cyclase.
       0.764
cpu_23240
L-serine dehydratase, iron-sulfur-dependent subunit beta.
  
  
 
0.761
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
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