STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (304 aa)    
Predicted Functional Partners:
cpu_07950
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.999
cpu_07960
Homoserine dehydrogenase.
  
 0.999
cpu_07930
Aspartate kinase; Belongs to the aspartokinase family.
  
 0.958
ilvE
Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.925
cpu_16440
Serine O-acetyltransferase.
     
 0.920
cpu_10040
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
    
 0.911
cpu_07880
O-acetylhomoserine aminocarboxypropyltransferase.
    
  0.910
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.910
cpu_06290
O-acetylhomoserine/O-acetylserine sulfhydrylase.
    
  0.891
cpu_07970
Hypothetical protein; Belongs to the UPF0735 family.
    
  0.869
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
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