STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpu_09200acyl-CoA synthetase. (544 aa)    
Predicted Functional Partners:
cpu_09930
Hypothetical protein.
   
 
 0.926
cpu_00450
acetyl-CoA synthase.
    
 0.895
cpu_09650
Citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.895
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
   
 
 0.895
cpu_24170
Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.895
cpu_23100
acyl-CoA dehydrogenase.
   
 
 0.894
cpu_09940
acetyl-CoA synthase subunit gamma.
   
 
 0.890
accA
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
    
  0.888
cpu_09970
acetyl-CoA synthase subunit delta.
   
 
 0.884
cpu_07390
3-methyl-2-oxobutanoate dehydrogenase subunit VorB.
 
 
 0.879
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.