| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cpu_04220 | cpu_16530 | cpu_04220 | cpu_16530 | MerR family transcriptional regulator. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.577 |
| cpu_04220 | dnaJ | cpu_04220 | cpu_05530 | MerR family transcriptional regulator. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.978 |
| cpu_04220 | grpE | cpu_04220 | cpu_05510 | MerR family transcriptional regulator. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.578 |
| cpu_04220 | htpX | cpu_04220 | cpu_13860 | MerR family transcriptional regulator. | Protease HtpX; Belongs to the peptidase M48B family. | 0.590 |
| cpu_10960 | grpE | cpu_10960 | cpu_05510 | Flagellar motor switch protein FliM. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.429 |
| cpu_10960 | htpX | cpu_10960 | cpu_13860 | Flagellar motor switch protein FliM. | Protease HtpX; Belongs to the peptidase M48B family. | 0.594 |
| cpu_11510 | htpX | cpu_11510 | cpu_13860 | DNA polymerase/3'-5' exonuclease PolX. | Protease HtpX; Belongs to the peptidase M48B family. | 0.456 |
| cpu_13840 | cpu_13850 | cpu_13840 | cpu_13850 | Hypothetical protein. | Hypothetical protein. | 0.773 |
| cpu_13840 | htpX | cpu_13840 | cpu_13860 | Hypothetical protein. | Protease HtpX; Belongs to the peptidase M48B family. | 0.496 |
| cpu_13850 | cpu_13840 | cpu_13850 | cpu_13840 | Hypothetical protein. | Hypothetical protein. | 0.773 |
| cpu_13850 | htpX | cpu_13850 | cpu_13860 | Hypothetical protein. | Protease HtpX; Belongs to the peptidase M48B family. | 0.496 |
| cpu_16530 | cpu_04220 | cpu_16530 | cpu_04220 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | MerR family transcriptional regulator. | 0.577 |
| cpu_16530 | dnaJ | cpu_16530 | cpu_05530 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.955 |
| cpu_16530 | ftsH | cpu_16530 | cpu_25100 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.478 |
| cpu_16530 | grpE | cpu_16530 | cpu_05510 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.928 |
| cpu_16530 | htpX | cpu_16530 | cpu_13860 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Protease HtpX; Belongs to the peptidase M48B family. | 0.518 |
| cpu_22330 | dnaJ | cpu_22330 | cpu_05530 | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.436 |
| cpu_22330 | htpX | cpu_22330 | cpu_13860 | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Protease HtpX; Belongs to the peptidase M48B family. | 0.449 |
| dnaJ | cpu_04220 | cpu_05530 | cpu_04220 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | MerR family transcriptional regulator. | 0.978 |
| dnaJ | cpu_16530 | cpu_05530 | cpu_16530 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.955 |