STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpu_15340Hydrogenase. (280 aa)    
Predicted Functional Partners:
cpu_15330
Sulfite reductase.
 
 0.998
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.990
cpu_15320
Dehydrogenase.
 
   
 0.935
cpu_06270
Putative sulfite reductase, iron-sulfur binding subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.909
cpu_17420
Sulfite reductase, dissimilatory-type beta subunit.
    
 0.903
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.903
pyrC
Hypothetical protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
 
 0.903
cpu_08730
Homotetrameric glutamate synthase (NADPH).
 
 0.891
cpu_12450
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 
  0.888
cpu_17430
Sulfite reductase, dissimilatory-type subunit alpha.
    
 0.884
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.