Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpu_21660DNA-binding response regulator. (228 aa)    
Predicted Functional Partners:
cpu_03310
ABC transporter substrate-binding protein.
 
 0.988
cpu_21650
Two-component sensor histidine kinase.
 
 0.979
cpu_20790
HDIG domain-containing protein.
  
 0.974
cpu_06990
Two-component sensor histidine kinase.
 
 0.926
cpu_07650
Sensor histidine kinase.
 
 0.919
cpu_03080
Sensory box histidine kinase.
 0.912
cpu_13990
Two-component sensor histidine kinase.
 
 0.832
cpu_04770
NADH dehydrogenase.
   
 
 0.813
cpu_15350
PAS domain-containing sensor histidine kinase.
  
 
 0.810
cpu_01470
Sensory box histidine kinase.
  
 
 0.797
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
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