cpu_22070 protein (Carboxydothermus pertinax)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

cpu_22070

Hypothetical protein. (165 aa)

Predicted Functional Partners:

rpmF

0.993

rpsC

0.943

rplK

0.934

rpsP

0.837

rplA

0.825

rplC

0.823

rpsF

0.817

rpsD

0.817

rpsB

0.816

infC

0.815

Your Current Organism:

Carboxydothermus pertinax

NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cpu_22070	infC	cpu_22070	cpu_11600	Hypothetical protein.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.815
cpu_22070	rplA	cpu_22070	cpu_25340	Hypothetical protein.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.825
cpu_22070	rplC	cpu_22070	cpu_23330	Hypothetical protein.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.823
cpu_22070	rplK	cpu_22070	cpu_25350	Hypothetical protein.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.934
cpu_22070	rpmF	cpu_22070	cpu_22060	Hypothetical protein.	50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.993
cpu_22070	rpsB	cpu_22070	cpu_19710	Hypothetical protein.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.816
cpu_22070	rpsC	cpu_22070	cpu_23380	Hypothetical protein.	30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.943
cpu_22070	rpsD	cpu_22070	cpu_23570	Hypothetical protein.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.817
cpu_22070	rpsF	cpu_22070	cpu_16640	Hypothetical protein.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.817
cpu_22070	rpsP	cpu_22070	cpu_21860	Hypothetical protein.	30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.837
infC	cpu_22070	cpu_11600	cpu_22070	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	Hypothetical protein.	0.815
infC	rplA	cpu_11600	cpu_25340	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.963
infC	rplC	cpu_11600	cpu_23330	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.967
infC	rplK	cpu_11600	cpu_25350	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.968
infC	rpmF	cpu_11600	cpu_22060	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.853
infC	rpsB	cpu_11600	cpu_19710	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.979
infC	rpsC	cpu_11600	cpu_23380	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.987
infC	rpsD	cpu_11600	cpu_23570	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.951
infC	rpsF	cpu_11600	cpu_16640	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.985
infC	rpsP	cpu_11600	cpu_21860	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.949