STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0C3JAE3NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (733 aa)    
Predicted Functional Partners:
A0A0C3JFA6
Flavodoxin-like domain-containing protein.
 
0.982
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
    
 0.931
A0A0C3JY49
Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
    
 0.926
A0A0C3N3Q5
Uncharacterized protein.
   
 0.886
A0A0C3JYR8
2Fe-2S ferredoxin-type domain-containing protein.
   
 0.873
A0A0C3NHF8
Sensitive to high expression protein 9, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology.
 
    
 0.849
A0A0C3JJV8
Hcy-binding domain-containing protein.
  
 0.848
A0A0C3PTF5
PAPS_reduct domain-containing protein.
  
 
 0.816
A0A0C3PYS8
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
    
 0.802
A0A0C3JPT0
PAPS_reduct domain-containing protein.
  
 
 0.790
Your Current Organism:
Pisolithus tinctorius
NCBI taxonomy Id: 870435
Other names: P. tinctorius Marx 270, Pisolithus tinctorius ATCC MYA-4688, Pisolithus tinctorius Marx 270
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