STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M404DRAFT_9087POLXc domain-containing protein. (486 aa)    
Predicted Functional Partners:
A0A0C3PH45
Uncharacterized protein.
    
 0.908
A0A0C3P5D3
DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.
  
 0.869
A0A0C3PGM1
Uncharacterized protein.
    
 0.864
A0A0C3KMY6
DNA ligase.
  
 0.863
A0A0C3PJG1
Uncharacterized protein.
  
 0.852
A0A0C3PH41
DNA_LIGASE_A3 domain-containing protein.
  
 0.843
A0A0C3PV42
SAP domain-containing protein.
    
 0.824
A0A0C3J954
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.811
A0A0C3JNX3
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.811
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.778
Your Current Organism:
Pisolithus tinctorius
NCBI taxonomy Id: 870435
Other names: P. tinctorius Marx 270, Pisolithus tinctorius ATCC MYA-4688, Pisolithus tinctorius Marx 270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.