STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
A0A0C3PFW0Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (518 aa)    
Predicted Functional Partners:
A0A0C3PCC7
Pterin-binding domain-containing protein.
  
 
 0.892
A0A0C3PS23
HPPK domain-containing protein.
  
 
 0.892
A0A0C3IM42
Thymidylat_synt domain-containing protein.
     
 0.867
A0A0C3J4S0
Thymidylat_synt domain-containing protein.
     
 0.867
A0A0C3NRV3
Thymidylat_synt domain-containing protein.
     
 0.867
M404DRAFT_8921
Flavoprotein domain-containing protein.
     
 0.867
A0A0C3PWV9
FSH1 domain-containing protein.
     
 0.861
A0A0C3J5S6
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.845
A0A0C3JFH0
Mur_ligase_M domain-containing protein.
  
  
0.844
A0A0C3PLK9
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.804
Your Current Organism:
Pisolithus tinctorius
NCBI taxonomy Id: 870435
Other names: P. tinctorius Marx 270, Pisolithus tinctorius ATCC MYA-4688, Pisolithus tinctorius Marx 270
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