STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0C3PWE5Autophagy-related protein. (123 aa)    
Predicted Functional Partners:
A0A0C3KMR9
Uncharacterized protein.
   
 0.999
A0A0C3PX56
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 0.999
A0A0C3P9L1
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.
   
 0.998
A0A0C3P7S8
Autophagy-related protein 3.
  
 0.997
A0A0C3PQ67
Protein kinase domain-containing protein.
   
 0.997
A0A0C3PWA7
Rab-GAP TBC domain-containing protein.
   
 0.991
A0A0C3PL09
Uncharacterized protein.
   
 0.984
A0A0C3JQP6
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 0.965
A0A0C3NUE6
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
   
 0.960
A0A0C3PF39
Uncharacterized protein.
    
 0.957
Your Current Organism:
Pisolithus tinctorius
NCBI taxonomy Id: 870435
Other names: P. tinctorius Marx 270, Pisolithus tinctorius ATCC MYA-4688, Pisolithus tinctorius Marx 270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.