STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SHG40736.13-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)    
Predicted Functional Partners:
SHG40778.1
[acyl-carrier-protein] S-malonyltransferase.
  0.952
SHH54662.1
Acyl transferase domain-containing protein.
  
 0.888
SHH48209.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.837
SHG29399.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  0.765
SHG50470.1
3-oxoacyl-[acyl-carrier-protein] synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  0.756
SHG40578.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  0.747
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
  0.724
fabH
3-oxoacyl-[acyl-carrier-protein] synthase-3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
  0.689
SHH54579.1
Natural product biosynthesis luciferase-like monooxygenase domain-containing protein.
  
 0.666
SHG48027.1
NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
  0.656
Your Current Organism:
Cognatishimia maritima
NCBI taxonomy Id: 870908
Other names: C. maritima, CCUG 60021, DSM 28223, KCTC 23347, Thalassobius maritima, Thalassobius maritimus, Thalassobius maritimus Park et al. 2012, Thalassobius sp. GSW-6, Thalassobius sp. GSW-M6, strain GSW-M6
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