node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHG35132.1 | SHG42878.1 | SAMN04488044_0535 | SAMN04488044_0754 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein. | 0.873 |
SHG35132.1 | SHH41457.1 | SAMN04488044_0535 | SAMN04488044_2477 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.637 |
SHG35132.1 | SHH43479.1 | SAMN04488044_0535 | SAMN04488044_2531 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA translocase FtsK. | 0.481 |
SHG35132.1 | dnaA | SAMN04488044_0535 | SAMN04488044_2476 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.975 |
SHG35132.1 | gyrB | SAMN04488044_0535 | SAMN04488044_2479 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.407 |
SHG35132.1 | recF | SAMN04488044_0535 | SAMN04488044_2478 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.438 |
SHG35132.1 | recR | SAMN04488044_0535 | SAMN04488044_2206 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.774 |
SHG42878.1 | SHG35132.1 | SAMN04488044_0754 | SAMN04488044_0535 | Hypothetical protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.873 |
SHG42878.1 | SHG99802.1 | SAMN04488044_0754 | SAMN04488044_1787 | Hypothetical protein. | Chromosome partitioning protein. | 0.401 |
SHG42878.1 | SHH41457.1 | SAMN04488044_0754 | SAMN04488044_2477 | Hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.996 |
SHG42878.1 | dnaA | SAMN04488044_0754 | SAMN04488044_2476 | Hypothetical protein. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.705 |
SHG42878.1 | recF | SAMN04488044_0754 | SAMN04488044_2478 | Hypothetical protein. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.799 |
SHG99757.1 | SHG99802.1 | SAMN04488044_1786 | SAMN04488044_1787 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | Chromosome partitioning protein. | 0.998 |
SHG99757.1 | SHH43479.1 | SAMN04488044_1786 | SAMN04488044_2531 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | DNA translocase FtsK. | 0.772 |
SHG99757.1 | SHH47852.1 | SAMN04488044_1786 | SAMN04488044_2631 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | DNA-binding protein HU-beta; Belongs to the bacterial histone-like protein family. | 0.402 |
SHG99757.1 | dnaA | SAMN04488044_1786 | SAMN04488044_2476 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.696 |
SHG99757.1 | recR | SAMN04488044_1786 | SAMN04488044_2206 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.456 |
SHG99802.1 | SHG42878.1 | SAMN04488044_1787 | SAMN04488044_0754 | Chromosome partitioning protein. | Hypothetical protein. | 0.401 |
SHG99802.1 | SHG99757.1 | SAMN04488044_1787 | SAMN04488044_1786 | Chromosome partitioning protein. | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | 0.998 |
SHG99802.1 | SHH43479.1 | SAMN04488044_1787 | SAMN04488044_2531 | Chromosome partitioning protein. | DNA translocase FtsK. | 0.637 |