STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHH58929.1DNA-binding transcriptional regulator, MerR family. (122 aa)    
Predicted Functional Partners:
SHH48209.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.851
SHG59783.1
PAS domain S-box-containing protein.
    
 0.728
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.724
SHH75061.1
DnaJ domain-containing protein; Manually curated.
  
 
 0.724
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.722
SHH58859.1
Acyl-coenzyme A thioesterase PaaI, contains HGG motif.
  
    0.718
SHH58896.1
Uncharacterized domain 1-containing protein.
  
    0.717
SHH58817.1
Multidrug resistance protein, MATE family.
       0.711
SHH58971.1
Transcriptional regulator, MerR family.
 
    
0.668
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.610
Your Current Organism:
Cognatishimia maritima
NCBI taxonomy Id: 870908
Other names: C. maritima, CCUG 60021, DSM 28223, KCTC 23347, Thalassobius maritima, Thalassobius maritimus, Thalassobius maritimus Park et al. 2012, Thalassobius sp. GSW-6, Thalassobius sp. GSW-M6, strain GSW-M6
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.