Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pntAForms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)    
Predicted Functional Partners:
pntB
Pyridine nucleotide transhydrogenase; Catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
BG60_13765
NAD synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
BG60_37975
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.942
BG60_13770
NAD(P) transhydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.857
ppnK
Inorganic polyphosphate kinase; Catalyzes the phosphorylation of NAD to NADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.793
nadE
NAD synthetase; Catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.774
BG60_04545
NAD-dependent deacetylase; Modulates the activities of several enzymes which are inactive in their acetylated form; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.765
BG60_29175
Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.764
BG60_25000
NAD synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.760
BG60_08700
Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.756
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.