Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BG60_01880hydroxymethylglutaryl-CoA lyase; Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)    
Predicted Functional Partners:
BG60_16930
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.956
BG60_01875
3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.924
BG60_36920
methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.908
BG60_06500
enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.902
BG60_36915
3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.856
BG60_18835
acetoacetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.834
BG60_05185
succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.819
BG60_25565
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.815
BG60_05180
succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.809
BG60_05070
3-oxoadipate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.803
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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