Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BG60_03560Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)    
Predicted Functional Partners:
BG60_14850
Ketol-acid reductoisomerase; Catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.952
BG60_14415
Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.927
BG60_14845
Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.907
BG60_26880
Catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.885
BG60_13205
2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.858
BG60_16930
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.846
BG60_14840
Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.840
BG60_29765
RpiR family transcriptional regulator; Glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.808
BG60_02150
Isopropylmalate isomerase; Dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.770
BG60_01450
Isopropylmalate isomerase; Dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.769
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.