Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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Experiments
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[Homology]
Score
BG60_04190cobalt-precorrin-6X reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)    
Predicted Functional Partners:
BG60_04180
precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
BG60_04185
cobalt-precorrin-6A synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
BG60_04160
precorrin-3B C17-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.998
BG60_04195
Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
BG60_04165
Catalyzes the formation of precorrin-3 from precorrin-2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
BG60_04170
Precorrin isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
BG60_11430
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.969
BG60_11460
Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.878
BG60_04110
Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.859
BG60_04135
Cobalamin biosynthesis protein CobN; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.856
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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