Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BG60_096602-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)    
Predicted Functional Partners:
BG60_05515
Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.880
BG60_15980
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.853
BG60_16695
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.814
BG60_06075
Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.782
BG60_16600
Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.782
BG60_23000
Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.782
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.782
BG60_14355
succinate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.756
BG60_20340
Carboxyvinyl-carboxyphosphonate phosphorylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.747
BG60_06000
2-methylisocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.726
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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