Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BG60_13850Preprotein translocase subunit SecD; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)    
Predicted Functional Partners:
BG60_13845
Preprotein translocase subunit SecF; Derived by automated computational analysis using gene prediction method: Protein Homology.
0.999
BG60_12050
Insertase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.989
BG60_13855
Preprotein translocase subunit YajC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.980
secY
Preprotein translocase subunit SecY; Forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.968
BG60_15625
Preprotein translocase subunit SecE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.963
BG60_15980
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.908
secA
Preprotein translocase subunit SecA; Functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not es [...]
  
 
 0.902
putA
Transcriptional regulator; Proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.878
BG60_05125
phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.874
BG60_13060
Preprotein translocase subunit SecB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.859
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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