Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BG60_13990HrcA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)    
Predicted Functional Partners:
BG60_14010
Heat shock protein GrpE; With DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.958
BG60_14020
Molecular chaperone DnaJ; Chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.839
BG60_06745
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.809
dnaK
Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.780
BG60_13980
DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.779
BG60_13995
Ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.753
ppnK
Inorganic polyphosphate kinase; Catalyzes the phosphorylation of NAD to NADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.681
groEL-2
Molecular chaperone GroEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; Derived by autom [...]
  
  
 0.660
BG60_27150
Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.630
BG60_17525
Molecular chaperone HscA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.599
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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