Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tmkThymidylate kinase; Catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)    
Predicted Functional Partners:
BG60_19140
DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.973
thyA
Thymidylate synthase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.960
BG60_24505
Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.941
BG60_32130
Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.932
BG60_19150
Aminodeoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.931
BG60_04010
Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.905
BG60_32155
Ribonucleotide-diphosphate reductase subunit beta; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.901
BG60_17330
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.873
BG60_24470
Stationary phase survival protein SurE; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.873
BG60_29190
Septum formation inhibitor Maf; Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.853
Your Current Organism:
Caballeronia zhejiangensis
NCBI taxonomy Id: 871203
Other names: Burkholderia sp. OP-1, Burkholderia zhejiangensis, C. zhejiangensis, CCTCC AB 2010354, Caballeronia zhejiangensis (Lu et al. 2012) Dobritsa and Samadpour 2016, DSM 28073, KCTC 23300, LMG 27258, LMG:27258, Paraburkholderia zhejiangensis, Paraburkholderia zhejiangensis (Lu et al. 2012) Sawana et al. 2015, strain OP-1
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